Cupramine™ is appropriate for treating a variety of external parasites of both freshwater and marine fish
Remove all invertebrates - these are extremely sensitive to copper and will not tolerate treatment with a copper-based medication. Turn off UV filters, ozone filters, and remove chemical filtration
If the bottle has a dropper cap, use 20 drops (1 mL) per 40 L (10.5 US gallons) the first day, wait 48 hours, then repeat. On non-dropper caps, each inner ring is 1 mL. In freshwater use half dose. Final copper concentration is 0.5 mg/L (0.25 mg/L in freshwater). Leave at this concentration for 14 days. Do not redose without testing (MultiTest™ Copper). If tank has ever been treated with an ionic copper (e.g. copper chloride, sulfate or citrate), test copper level after initial dosing. Although most fish tolerate Cupramine™ to 0.8 mg/L, it is not advisable to exceed 0.6 mg/L copper.